The Comic Book Shoppe is based in Ottawa, Ontario, Canada, and is comprised of three separate locations: The Comic Book Shoppe 2 downtown on Bank Street, The Anime Stop in the west end on Clyde, and the original Comic Book Shoppe right next door to them also on Clyde.

While the Anime Stop specializes in Anime, Manga and related figures and collectibles, the Comic Book Shoppe on Clyde specializes in comics, toys, figures, board games and collectibles, as well as licensed apparel. The Comic Book Shoppe on Bank street combines both of these in one location.